Trinity College Dublin is the top ranked University in Ireland. Immunology is one of the priority research themes in TCD, and activity within the School of Biochemistry and Immunology very significantly contributes to the ranking of Ireland as 2nd in the world for Immunology research. The School has a global reputation for research in innate immunity, viral sensing and more recently immunometabolism (www.tcd.ie/Biochemistry), and is part of the Trinity Biomedical Sciences Institute (www.tcd.ie/biosciences). Expertise in postgraduate training is reflected in the fact that the School runs the only dedicated MSc in Immunology in Ireland, and has approx. 80 PhD students in training at any one time. The TCD research groups thus provide an excellent training environment for PhD students wanting to work at the cutting edge of Immunology research.
Prof. Bowie is a Professor of Innate Immunology in the School of Biochemistry and Immunology. His research focuses on innate immune sensing and signalling mechanisms, and their modulation by viruses. His group also investigates how pattern recognition receptors (PRRs) and inflammasomes drive inflammation through the recognition of ‘stranger’ and ‘danger’ signals (such as dsDNA).
Prof. O’Neill is the Chair of Biochemistry and Head of Immunology in the School of Biochemistry and Immunology. His current research is focused on the molecular and cellular basis to inflammation and innate immunity. Specific aspects include Toll-like receptors; Pro-inflammatory cytokines; Inflammasomes; Molecular analysis of inflammatory and infectious diseases; Immunometabolism and Metabolic Reprogramming in Innate Immunity.
Prof. O’Farrelly is Professor of Comparative Immunology and her research focuses on innate anti-viral and anti-tumour immunity, particularly in human liver. Prof. O’Farrelly has supervised or co-supervised 40 PhD students and was awarded the Nature Mentoring Award in 2014. She is co-director of the MSc in Immunology at TCD and has led the development of a new MSc in Immunotherapeutics.