Prof. O’Neill is the Chair of Biochemistry and Head of Immunology in the School of Biochemistry and Immunology. His current research is focused on the molecular and cellular basis to inflammation and innate immunity.  Specific aspects include Toll-like receptors; Pro-inflammatory cytokines; Inflammasomes; Molecular analysis of inflammatory and infectious diseases; Immunometabolismand Metabolic Reprogramming in Innate Immunity.